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October 8, 2014

Natural product-based therapy for Mammary Cancer: Silvestrol, a compound isolated from the fruits of Aglaia foveolata, suppresses Mammary cancer cell migration and invasion via down regulation of Receptor for hyaluronan-mediated motility (RHAMM)/Hyaluronan-mediated motility receptor (HMMR), 8/October/2014, 17.00

A study from the School of Life Sciences, Tsinghua University, Beijing 100084, China shows that “Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility.” […]
October 8, 2014

Natural product-based therapy for Human Cancer: Triptolide, a natural compound isolated from Thunder of God vine, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene, 8/October/2014, 16.54

The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; I.F: >35) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This […]
October 8, 2014

MiRNA-based therapy for Osteoporosis and its related disorders: Progestin inhibits osteoporosis and skeletal ageing by inhibiting the Wnt4 pathway, Genome-2-Bio-Medicine Discovery center (GBMD), 8/October/2014, 10.23 am

A recent study from the Laboratory of Molecular Signaling, University of California Los Angeles, Los Angeles, California, USA shows that “Wnt4 signaling prevents skeletal aging and inflammation by inhibiting […]
October 8, 2014

Small molecule therapy for Myocardial Infarction: Alpha-lipoic acid improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 8/October/2014, 7.13 am

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March   2013 issue of Nature  by Prof Dimmler, […]
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