Therapeutic insights into restoring the contractility of heart muscle function during heart failure: Ginsenoside Rb₁ improves cardiac contractility and function via down regulation of its target gene, 27/April/2014, 5.46 am
A study from University of California, San Diego, and Sanford-Burnham Medical Research Institute, La Jolla, California, USA shows that Inhibition of miR-25 improves cardiac contractility in the failing heart. This study was published in the April 24, 2014 Nature by Prof. Dr Mark Mercola and others from the Department of Bioengineering, University of California, San Diego, and the Muscle Development and Regeneration Program, Sanford-Burnham […]
Insight into the treatment of Metastatic Pancreatic/intestine/ovarian Cancer: C/EBPzeta (CHOP/Gadd153) suppresses the expression of PDGF Receptor β via up regulation of its target gene, 26/April/2014, 8.56 am
A study from Watson School of Biological Sciences shows that Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β (Pdgfrβ) Signaling. This study was published in the April 10, 2014 Cell by Prof. Dr Scott Lowe, Watson School of Biological Sciences, CSHL, New York; Prof. Dr Carol Prives, Department of Biological Sciences, Columbia University, New York; and others. On the foundation […]
Mechanistic insights into p53-activated tumor suppressor network in human cancer cells: Tumor suppressor p53 suppresses the expression of SPOP via up regulation of its target gene, 26/April/2014, 8.40 am
A recent study from University of Chicago (Illinois, USA) shows “SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub…” This study was published in the prestigious Journal “Cancer Cell (One of the top journal in Cancer Biology).” On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Mechanistic insights into p53-activated tumor suppressor network in […]
Mechanistic insight into Hypoxia-induced tumorigenesis, invasion and metastasis: HIF-1α suppresses the expression of tumor suppressor TIMP3 via up regulation of its target miRNA, 26/April/2014, 7.17 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Mechanistic insight into Hypoxia-induced tumorigenesis, invasion and metastasis: HIF-1α suppresses the expression of tumor suppressor TIMP3 via up regulation of its target miRNA, 26/April/2014, 7.17 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation
Mechanistic insight into Hypoxia-induced tumorigenesis, invasion and metastasis: HIF-1α suppresses the expression of tumor suppressor GRHL3 via up regulation of its target miRNA, 26/April/2014, 7.13 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Mechanistic insight into Hypoxia-induced tumorigenesis, invasion and metastasis: HIF-1α suppresses the expression of tumor suppressor GRHL3 via up regulation of its target miRNA, 26/April/2014, 7.13 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation
Mechanistic insight into Hypoxia-induced tumorigenesis, invasion and metastasis: HIF-1α suppresses the expression of tumor suppressor INK4a/p16 via up regulation of its target miRNA, 26/April/2014, 7.10 am
Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Mechanistic insight into Hypoxia-induced tumorigenesis, invasion and metastasis: HIF-1α suppresses the expression of tumor suppressor INK4a/p16 via up regulation of its target miRNA, 26/April/2014, 7.10 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org * Research cooperation