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May 27, 2018

A glycolipid comes to rescue of blood sugar disease: α-Galactosylceramide-based regenerative therapy for reversing diabetes:  α-Galactosylceramide (α-GalCer), a synthetic glycolipid derived from Agelas mauritanius, increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 27/May/2018, 11.34 am

Introduction: What they say A study from the Longevity Institute, School of Gerontology, Department of Biological Sciences, University of Southern California, 3715 McClintock Avenue, Los Angeles, […]
May 27, 2018

Sleeping your way to say no to cardiac diseases: Melatonin-based therapy for attenuating pathogenesis-associated with Myocardial infarction: Melatonin, a hormone known to play a role in sleep and wakefulness, decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up regulation of its target gene, 27/May/2018, 7.21 am

Introduction: What they say: A recent study from Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA; and Cardiovascular Research Center, Massachusetts General Hospital and […]
May 27, 2018

Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Hydrogen-rich saline increases the expression of tumor suppressors genes, such as  p53, TA-p73 and TA-p63, BTG2 and INK4a, and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 27/May/2017, 7.02 am

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
May 27, 2018

Serotonin the happy hormone comes to the rescue of blood sugar disease: Serotonin-based adjunct therapy for autoimmune diabetes (TIDM): Serotonin (5-hydroxytryptamine (5-HT)), a mono neurotransmitter known to play a role in mood, anxiety and depression, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 27/May/2018, 6.41 am

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical […]
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