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August 22, 2014

Therapeutic and Mechanistic insights into tumor suppression: BMP-4 (Bone Morphogenetic protein-4) inhibits tumorigenesis via up regulation of Sin3b, Hbp1, Suv420h1, Btg1 & BIM, Genome-2-Bio-Medicine Discovery center (GBMD), 22/08/2014, 8.09 am

A study from the Division of Oncology, Department of Medicine/Pathology, Stanford University, Stanford, California, USA shows that “MYC through miR-17-92 Suppresses Specific Target Genes to Maintain Survival, Autonomous Proliferation…” This […]
August 22, 2014

Therapeutic insights into enhancing the radiosensitivity of tumor cells: Metformin, the widely used drug in the treatment of NIDDM, enhances radiosensitivity of tumor cells via down regulation of ATM and ZEB1, Genome-2-Bio-Medicine Discovery center (GBMD), 22/08/2014, 6.35 am

A study from the Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA shows that “ATM-mediated stabilization of ZEB1 promotes DNA damage response […]
August 22, 2014

Yoga therapy for Myocardial disorders: Nisshesha rechaka pranayama (Brief Intermittent Hypoxia) improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10(Serine/threonine-protein phosphatase 1 regulatory subunit 10), 22/August/2014, 6.31 am

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the March 7  2013 Nature  by Prof Dimmler, Boon, and others. On […]
August 22, 2014

AntagomiR-based treatment for T2D: miRNA-199a-3p decreases insulin sensitivity via down regulation of a regulator of insulin receptor, Caveolin-1, 22/08/2014, 06.04 am

A study from the Institute for Molecular Systems Biology, ETH Zurich, Zurich, Switzerland shows that “MicroRNAs 103 and 107 regulate insulin sensitivity.” This study was published in the June 8, 2011 Nature [I.F >35] by Prof. Stoffel M, Trajkovski […]
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