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October 8, 2014

Interleukin-based Anti-Cancer Stem cell therapy: Interleukin-1β (IL-1β) suppresses the expression of Nucleoplasmin and reprogramming of somatic cells via down regulation of its target gene, 9/October/2014, 5.06 am

The 1989 Nobel prize winner in Physiology/Medicine, Prof. Bishop JM, Qu J and others from G.W. Hooper Foundation, University of California at San Francisco, San Francisco, California 94143, USA has published a research paper in the 11 June […]
October 8, 2014

Natural product-based therapy for Mammary Cancer: Silvestrol, a compound isolated from the fruits of Aglaia foveolata, suppresses Mammary cancer cell migration and invasion via down regulation of Receptor for hyaluronan-mediated motility (RHAMM)/Hyaluronan-mediated motility receptor (HMMR), 8/October/2014, 17.00

A study from the School of Life Sciences, Tsinghua University, Beijing 100084, China shows that “Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility.” […]
October 8, 2014

Natural product-based therapy for Human Cancer: Triptolide, a natural compound isolated from Thunder of God vine, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene, 8/October/2014, 16.54

The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; I.F: >35) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This […]
October 8, 2014

MiRNA-based therapy for Osteoporosis and its related disorders: Progestin inhibits osteoporosis and skeletal ageing by inhibiting the Wnt4 pathway, Genome-2-Bio-Medicine Discovery center (GBMD), 8/October/2014, 10.23 am

A recent study from the Laboratory of Molecular Signaling, University of California Los Angeles, Los Angeles, California, USA shows that “Wnt4 signaling prevents skeletal aging and inflammation by inhibiting […]
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