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March 10, 2020
Published by admin_auro at March 10, 2020
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Mechanistic insights into how Vitamin D3/Cholecalciferol enhances immunity against bacterial infections: Cholecalciferol-based immune enhancement therapy: Low dose Cholecalciferol/Vitamin-D3 increases SOX2 expression, and promotes innate immunity against bacterial infection, via down-regulation of its target gene, 10/March/2020, 6.18 am

Introduction: What they say:   A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in […]
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March 9, 2020
Published by admin_auro at March 9, 2020
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Repurposing the anti-hypertensive drug Carvedilol into an antiviral agent: Carvedilol (trade name: Coreg), increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication, via upregulation of its target gene, 10/March/2019, 12.02 am

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
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March 9, 2020
Published by admin_auro at March 9, 2020
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Antiviral therapy against Neuroinvasive West Nile virus: Zafirlukast, an anti-asthmatic drug, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 9/March/2020, 11.42 pm

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of […]
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March 9, 2020
Published by admin_auro at March 9, 2020
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Repurposing the anti-cancer agent Imatinib into an anti-HIV agent: Imatinib (trade name: Gleevec, Glivec and others) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 9/March/2020, 11.23 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Repurposing the anti-cancer agent Imatinib into an anti-HIV agent: Imatinib (trade name: Gleevec, […]
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