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July 1, 2014
Published by admin_auro at July 1, 2014
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MiRNA-based therapy for Human Cancer: MiRNA-217 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) via up regulation of its target gene, 1/July/2014, 10.25 am

The 1989 Noble prize winner in Chemistry, Prof. Thomas R. Cech from the University of Colorado BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; I.F: >35) stating that “The TEL patch of telomere protein TPP1 mediates […]
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July 1, 2014
Published by admin_auro at July 1, 2014
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Anti-miRNA based therapy for NIDDM: Increased expression of Stress-responsive miRNA-195 promotes gluconeogenesis and hyperglycemia via down regulation of Cyclin D1, 1/July/2014, 10.18 am

A study from the Department of Cancer Biology, Dana-Farber Cancer Institute;  Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA; and others shows that “Cyclin D1–Cdk4 controls glucose […]
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July 1, 2014
Published by admin_auro at July 1, 2014
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Mechanistic insights into allergen-induced tumorigenesis: Allergen suppresses the expression of tumor suppressor GRHL3 via up regulation of its target gene, 1/July/2014, 9.35 am

Idea Proposed/Formulated by: Dr L Boominathan PhD Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Mechanistic insights into allergen-induced tumorigenesis: Allergen suppresses the expression of tumor  suppressor GRHL3 via up regulation of its […]
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July 1, 2014
Published by admin_auro at July 1, 2014
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Molecular cancer therapy: Endothelin-1 inhibits cancer development by suppressing the expression of nucleotide sanitizing enzyme MTH1/NUDT1, 1/July/2014, 8.45 am

A study from Karolinska Institutet, Stockholm, Sweden shows that MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.  This study was published in the April 10, 2014 Nature [I.F >35] by Prof. Thomas H, […]
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