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August 10, 2018
Published by admin_auro at August 10, 2018
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Estrogen functions as a longevity promoter: Estrogen, a female steroid hormone, may  increase insulin sensitivity, slow down cardiac aging, and increase lifespan, via up-regulation of BubR1 and others genes, 10/August/2018, 10.27 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston, USA; […]
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August 10, 2018
Published by admin_auro at August 10, 2018
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I do more than what I intended for: Estrogen comes to the rescue of blood sugar disease: Estrogen, a female sex steroid hormone,  increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of  its target gene Lin28, 10/August/2018, 9.59 am

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
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August 10, 2018
Published by admin_auro at August 10, 2018
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Androgens come to the rescue of anxiety and depression: Testosterone, a male reproductive steroid hormone, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression, via down-regulation of its target gene, 10/August/2018, 9.45 am

Introduction: What they say:  A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
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August 8, 2018
Published by admin_auro at August 8, 2018
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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Emodin, isolated from Rhubarb and others,  increases the expression of tumor suppressors genes, such as SOCS1/6, TET1, TA-p73, TAp63, p53, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 8/August/2018, 10.23 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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