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March 5, 2018
Published by admin_auro at March 5, 2018
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Amino-acid based combinatorial therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing Glycine, Epicatechin and Matrine (GEM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 5/March/2018, 11.13 am

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for […]
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March 4, 2018
Published by admin_auro at March 4, 2018
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Amino acid-based therapy for diabetes (TIDM): Glycine, a non-essential amino acid and inhibitory neurotransmitter, increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 4/March/2018, 12.23 pm

Introduction: What they say   A study from the Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham, […]
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March 4, 2018
Published by admin_auro at March 4, 2018
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Polyamine-based Lifespan extension therapy: Spermidine prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 4/March/2018, 12.17 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
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March 4, 2018
Published by admin_auro at March 4, 2018
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Amino acid-based therapy for TIIDM and obesity-associated metabolic deficits: Glycine, a non-essential amino acid and inhibitory neurotransmitter,  increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 4/March/2018, 11.45 am

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent […]
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