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August 13, 2018
Published by admin_auro at August 13, 2018
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An aspirin a day keeps HIV1-infections at bay: Aspirin, an analgesic/antipyretic drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via upregulation of its target gene, 13/August/2018, 6.28 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: An aspirin a day keeps HIV1-infections at bay: Aspirin, an analgesic/antipyretic drug, increases Heme […]
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August 13, 2018
Published by admin_auro at August 13, 2018
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Birth control/contraceptive pills as anti-infective agents:  17-α-Ethynylestradiol, one of the main components of contraceptive/birth control pills, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene 131/August/2018, 6.11 pm

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]
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August 11, 2018
Published by admin_auro at August 11, 2018
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Steroid hormone may attenuate arthritic pain: Progesterone (P4)-based therapy for inflammation and arthritis:Progesterone (P4), an endogenous steroid that plays a role in the menstrual cycle, pregnancy, embryogenesis, and others, increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up-regulation of its target genes, 11/August/2018, 10.41 pm

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that […]
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August 11, 2018
Published by admin_auro at August 11, 2018
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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Emodin, isolated from Rhubarb and others,  increases the expression of tumor suppressors genes, such as  RhoB, p57Kip2, TA-p73, TAp63, p53, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 11/August/2018, 10.17 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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