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May 22, 2018

A salty way to say no to cardiac diseases-hard to believe though (!): Hypertonic saline-based therapy for attenuating pathogenesis-associated with Myocardial infarction: Hypertonic saline (10%) decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up regulation of its target gene, 22/May/2018, 3.45 pm

Introduction: What they say: A recent study from Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA; and Cardiovascular Research Center, Massachusetts General Hospital and […]
May 20, 2018

Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Hydrogen-rich saline increases the expression of tumor suppressors genes, such as  p53, TA-p73 and TA-p63, TIMP3, and CCM3/KRIT1, and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 20/May/2017, 4.56 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
May 20, 2018

Molecular therapy for Deafness: A therapeutic mix encompassing Lactulose, Cholecalciferol, Ajoene and DIM (LCAD) increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 20/May/2018, 4.43 pm

  What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:   Molecular therapy for Deafness: A therapeutic mix encompassing Lactulose, Cholecalciferol, Ajoene and DIM (LCAD) increases the […]
May 20, 2018

Molecular therapy for cardiomyocyte proliferation and heart regeneration: A pharmaceutical mixture encompassing   3,3′-Diindolylmethane (DIM) Sodium nitrite(NaNO2), and  Sodium Sulfide (DIMSNSS) decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up regulation of its target gene, 20/May/2018, 4.29 pm

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory […]
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