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May 24, 2019

Mechanistic insights into how Pregabalin attenuates neuropathic pain: Pregabalin (Trade name: Lyrica), used to treat epilepsy, neuropathic pain, fibromyalgia, restless leg syndrome, and generalized anxiety disorder (GAD), increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 24/May/2019, 10.54  pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
May 24, 2019

Combinatorial therapy for autoimmune diabetes (TIDM):  A pharmaceutical mixture encompassing Prostaglandin E2 (PGE2) and Verapamil (VM) [PGE2VM] increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 24/Mat/2019, 10.42 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
May 23, 2019

Mechanistic insights into how Neurotropin (NTP) attenuates neuropathic pain: Neurotropin, derived from the  inflamed skin of rabbits inoculated with vaccinia virus, increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 23/May/2019, 10.47  pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
May 23, 2019

A commonly prescribed blood-pressure drug comes to the rescue of diabetes (TIIDM): Verapamil (brand name: Calan, Isoptin, and others), a calcium channel blocker used in the treatment of high blood pressure, angina, supraventricular tachycardia, migraines, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 23/May/2019, 10.31 pm

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
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