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May 27, 2018

Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Hydrogen-rich saline increases the expression of tumor suppressors genes, such as  p53, TA-p73 and TA-p63, BTG2 and INK4a, and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 27/May/2017, 7.02 am

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
May 27, 2018

Serotonin the happy hormone comes to the rescue of blood sugar disease: Serotonin-based adjunct therapy for autoimmune diabetes (TIDM): Serotonin (5-hydroxytryptamine (5-HT)), a mono neurotransmitter known to play a role in mood, anxiety and depression, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 27/May/2018, 6.41 am

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical […]
May 25, 2018

Sleeping your way to live free of cardiac diseases: Melatonin-based therapy for Cardiomyopathy: Melatonin ( N-acetyl-5-methoxy tryptamine), a hormone known to regulate sleep and wakefulness, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy, via up regulation of its target gene, 25/May/2018, 7.29 pm

Introduction: What they say   A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart […]
May 22, 2018

A salty way to keep the cardiac diseases at bay-hard to believe though(!): Hypertonic saline-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients:  Hypertonic saline (10%) increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes via down regulation of its target gene, 23/May/2018, 12.58 am

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
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