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July 12, 2019

Mechanistic insights into how Methylprednisolone(MPD) may function as a pain medication: Methylprednisolone(MPD),  used in the treatment of rheumatic disorders, asthma, allergies and others,  increases the expression of PD-L1, decreases the expression of Cox-2, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 12/July/2019, 10.26 pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
July 10, 2019

Little RNA can better your heart functioning: LncRNA Mirt2 -based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: LncRNA Mirt2 (Myocardial infarction-associated transcript 1 (Mirt1) increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via up-regulation of its target gene, 10/July/2019, 11.41 am

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
July 10, 2019

Natural product-based Lifespan extension therapy:  Polysaccharides, derived from Lycium barbarum L (LBL),  inhibit the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extend mammalian lifespan by regulating the expression of their target genes, 10/July/2019, 10.15 am

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
July 10, 2019

Little RNA may protect your heart from heart attack: Intracardiac injection of  LncRNA Mirt2 attenuates pathogenesis-associated with Myocardial infarction:  LncRNA Mirt2 decreases IRF3, GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leukocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up regulation of its target gene, 10/July/2019, 8.06 am

Introduction: What they say:  A recent study from Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA; and Cardiovascular Research Center, Massachusetts General Hospital and […]
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