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November 23, 2017

Combinatorial therapy for prostate cancer:  A therapeutic mix encompassing Calcitriol, Mitoxantrone, Despiramine, 17-DMAG, Salinomycin, Lovastatin, and Jasmonate (CMDDSLJ) inhibits the expression of mTORC1 and its downstream target AMD1, dismantles mTORC1-AMD1 signaling network, decreases polyamine levels, and inhibits prostate cancer progression via up regualtion of its target gene, 23/November/2017, 12.15 pm

Introduction: What they say: A study from CIC bioGUNE (Center for Cooperative Research in Biosciences), Bizkaia Technology Park, 801 Building, 48160 Derio, Spain shows that “mTORC1-dependent AMD1 regulation sustains polyamine […]
November 23, 2017

Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing  Safrnal, Catalpol, Cholecalciferol, Maresin, Ursolic acid, DIM, Isoliquiritigenin, & Lutein   (SCCMUDIL) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 23/Novem ber/2017, 7.40 am

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
November 22, 2017

Molecular therapy for glioblastoma: A therapeutic mix encompassing Temozolomide (TMZ), 17-AAG, Simvastatin, Salinomycin, Linalool, Amitriptyline (TASSLA) inhibits the expression of JMJD6, impairs functioning of transcription elongation machinery, inhibits the proliferation of glioblastoma cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 22/November/2017, 6.06 am

Introduction: What they say: A study from the Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Ohio, USA shows that “Transcription elongation factors […]
November 21, 2017

Natural product-derived combinatorial therapy for therapy-resistant cancers: A therapeutic mix encompassing encompassing   β-cryptoxanthin (BCX), Sodium butyrate, Fucoxanthin, Ganetespib, Rosuvastatin and Cyclophosphamide (BCXSFGRC) inhibits the expression of phospholipid glutathione peroxidase (GPX4), inhibits GPX4 signaling network and lipid peroxidase pathway, suppresses EMT protein ZEB1, increases sensitivity to anticancer therapy and prolongs survival via up regulation of its target gene, 21/November/2017, 10.49 pm

Introduction: What they say: A study from Broad Institute, Cambridge, Massachusetts, USA, Howard Hughes Medical Institute, Chevy Chase, Maryland and Department of Chemistry and Chemical Biology, […]
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