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November 17, 2017

Molecular therapy for Stroke:  Butylphthalide (3-n-butylphthalide or NBP), found in celery oil, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 17/November/2017, 5.54 am

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]
November 17, 2017

Natural product-based therapy for Deafness: A therapeutic mix encompassing Safranal, Cholecalciferol  and DIM (SCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  and improves hearing loss via up regulation of its target genes, 17/November/2017, 5.41 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-based therapy for Deafness: A therapeutic mix encompassing Safranal, Cholecalciferol  and DIM (SCAD)  increases the expression of […]
November 16, 2017

Natural product-derived therapy for anxiety and depression: Sedanolide, isolated from Celery/Apium graveolens Var. dulce, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 16/November/2017, 11.47 am

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
November 16, 2017

Molecular therapy for Diabetic nephropathy (DN):  Epalrestat, an aldose reductase inhibitor used in the treatment of Diabetes Nephropathy, increases Pyruvate kinase M2 (PKM2) expression, decreases toxic glucose metabolites, mitochondrial dysfunction and apoptosis, augments glycolytic flux and PGC-1α levels, improves metabolic abnormalities, albuminuria, glomerular pathology, and renal dysfunction and alleviates diabetic nephropathy via down regulation of its target gene, 16/November/2017, 10.35 am

Introduction: What they say A study from the Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA shows that “Pyruvate kinase M2 activation may protect against the […]
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