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November 8, 2017

Molecular therapy for heart regeneration and repair: A therapeutic mix encompassing Efonidipine and Verapamil, anti-hypertensive drugs, increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 8/November/2017, 11.43 pm

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, […]
November 8, 2017

Natural product therapy for body weight control, energy homeostasis and TIIDM:  Linalool, found in coriander oil, sweet orange (Citrus sinensis), tomato,  oils of rose, neroli, lavender, laurel and sweet basil (Ocimum basilicum) among others, decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 8/November/2017, 11.00 pm

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
November 8, 2017

Lifespan extension therapy: Amorfrutin A, isolated from Amorpha fruticosa L,  may increase life span via up-regulation of its target gene BubR1, 8/October/2017, 10.45 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
November 8, 2017

Natural product therapy for Non-alcoholic fatty liver disease (NAFLD): Hesperidin, isolated from Citrus fruits, promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 8/November/2017, 10.37 pm

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]
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