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April 10, 2018
Published by admin_auro at April 10, 2018
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Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Suramin (trade name: Moranyl, Naganin, Naganine and others), a drug used in the treatment of sleeping sickness and others, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 10/April/2018, 7.17 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
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April 10, 2018
Published by admin_auro at April 10, 2018
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Natural product-derived therapy for Metastatic human tumors: Solasodine, isolated from solanum melongena, decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 10/April/2018, 7.04 pm

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]
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April 10, 2018
Published by admin_auro at April 10, 2018
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Natural product-based therapy for CyclinD3-CDK6 overexpressing cancers: Nimbolide, isolated from Azadirachta indica, inhibits the activity of glycolytic enzymes 6-phosphofructokinase and pyruvate kinase M2, decreases antioxidants NADPH and glutathione levels, increases reactive oxygen species levels, promotes apoptosis, and inhibits the progression of CyclinD3-CDK6 overexpressing cancers via down regulation of its target gene, 10/April/2018, 6.41 pm

Introduction: What they say A study from Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA; and Department of Genetics, Harvard Medical School, Boston, Massachusetts, […]
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April 10, 2018
Published by admin_auro at April 10, 2018
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Natural product-based therapy for blood-stage Plasmodium infection: Moringin, isolated from moringa olifera, decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via up regulation of its target gene, 10/April/2018, 6.29 pm

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that […]
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