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March 27, 2018

Sugar-based anti-ageing and Lifespan extension therapy: Xylitol, an artificial sweetener used in drugs, confections, toothpaste and chewing gum,  increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 27/March/2018, 6.09 am

Introduction: What they say  A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]
March 27, 2018

Natural product-derived therapy for blood-stage Plasmodium infection: Linarin, isolated from mentha arvensis and Linaris vulgaris among others, decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria, via up regulation of its target gene, 27/March/2018, 5.59 am

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that […]
March 27, 2018

Sugar-based therapy for diabetes (TIIDM): Lactulose (brand name: Cholac, Generlac, Consulose, Duphalac), a drug used in the treatment of constipation and hepatic encephalopathy, increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 27/March/2018, 5.50 am

Introduction: What they say A study from the Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham, […]
March 27, 2018

Hormonal therapy for Glaucoma: Melatonin (N-acetyl-5-methoxy tryptamine), a hormone that regulates sleep and wakefulness, increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma via down regulation of its target gene, 27/March/2018, 5.41 am

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, […]
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