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March 16, 2018

A sweet way to extend lifespan: Sugar-based Lifespan extension therapy: D-Allulose/D-Psicose, a low-calorie sweetener isolated from natural products, may increase life span via up-regulation of its target gene BubR1, 16/March/2018, 6.50 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
March 16, 2018

Natural product-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Hesperidin, isolated from citrus aurantium, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 16/March/2018, 6.38 am

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
March 16, 2018

Amino acid-based therapy for Myocardial Infarction:  Tryptophan, an essential amino acid and precursor of the neurotransmitter serotonin and the sleep hormone melatonin, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up regulation of PNUTS, 16/March/2018, 6.26 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of […]
March 15, 2018

Sugar-based therapy for Metastatic cancers: Xylobiose, a disaccharide of xylose, increases the expression of tumor/metastatic suppressors TIMP3 and CCM3/KRIT1 , inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 15/March/2017, 11,23 pm

From Significance of the study to Public health relevance:  Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
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