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December 3, 2017

Molecular therapy for Deafness: A therapeutic mix encompassing Paroxetine, Cholecalciferol, Ajoene and DIM (PCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 3/December/2017, 10.26 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Molecular therapy for Deafness: A therapeutic mix encompassing Paroxetine, Cholecalciferol, Ajoene and DIM (PCAD)  increases the expression of […]
December 3, 2017

Natural product-derived therapy for Stroke: Eucalyptol, isolated from Eucalyptus globulus,  Cinnamomum camphora, Bay leaves, and Rosemary, among others, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 3/December/2017, 10.03 pm

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]
December 3, 2017

Molecular therapy for Myocardial Infarction: Cilostazol, a phosphodiesterase inhibitor used in the treatment of peripheral vascular disease,  inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 3/December/2017, 9.35 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of Nature,  by Prof Dimmler, […]
December 2, 2017

Molecular therapy for heart regeneration and repair: A therapeutic mix encompassing Aripiprazole and Cilostazol increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 2/December/2017, 8.39 am

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, […]
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