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December 27, 2017

Lifespan extension therapy: Hydralazine[Trade name: Apresoline], used in the treatment of high blood pressure and heart attacks,  increases life span via up-regulation of its target gene BubR1, 28/December/2017, 1.03 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
December 27, 2017

Natural product-based Anti-ageing and Life extension therapy:  A pharmaceutical mixture encompassing Apigenin and Chrysin increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 28/December/2017, 12.54 am

Introduction: What they say A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]
December 27, 2017

Molecular therapy for pulmonary arterial hypertension: Azilsartan[Brand name: Edarbi], an angiotensin II type 1 receptor blocker used in the treatment of high blood pressure, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 28/December/2017, 12.44 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
December 26, 2017

Natural product therapy for body weight control, energy homeostasis and TIIDM:Lycopene, isolated from Gac, Guava and Tomatoes,  decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 27/December/2017, 12.20 am

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
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