Dr.Boomi

September 5, 2017

Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Linalool, isolated from Lavender, among others, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 6/September/2017, 12.09 am

Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Linalool, isolated from Lavender, among others, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 6/September/2017, 12.09 am https://genomediscovery.org/wp-content/uploads/2017/09/Linalool-inhibits-CHIKV-and-ZIKV-through-up-regulation-of-SAT.jpg1_.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2017/09/Linalool-inhibits-CHIKV-and-ZIKV-through-up-regulation-of-SAT.jpg1_.jpg September 5, 2017 September 5, 2017

Teacher’s day special ********* We wish everyone a happy Teacher’s day. On this special occasion, we are happy to announce that ideas posted today (05/September/2017) will be available to the use of Scientists/Professors/Physicians/Researchers for free. So,…

September 5, 2017

Natural product-derived therapy for Metastatic human tumors: A pharmaceutical mixture encompassing Nimbolide and Curcumin decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 05/September/2017, 11.58 pm

Natural product-derived therapy for Metastatic human tumors: A pharmaceutical mixture encompassing Nimbolide and Curcumin decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 05/September/2017, 11.58 pm https://genomediscovery.org/wp-content/uploads/2017/09/Nimbolide-and-Curcumin-inhibits-cancer-metastasis-through-down-regulatino-of-cSrc-and-HK2.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2017/09/Nimbolide-and-Curcumin-inhibits-cancer-metastasis-through-down-regulatino-of-cSrc-and-HK2.jpg September 5, 2017 September 5, 2017

September 5, 2017

Natural product-derived antiviral therapy against Hepatitis-B virus: EGCG (Epigallocatechin gallate), found abundantly in Green tea, increases the expression of Setd2, methylates STAT1, activates STAT1, promotes trimethylation of IFN-stimulated gene-15, and restricts Hepatitis-B virus (HBV) production and pathogenesis via up regulation of its target gene, 05/September/2017, 11.53 am

Natural product-derived antiviral therapy against Hepatitis-B virus: EGCG (Epigallocatechin gallate), found abundantly in Green tea, increases the expression of Setd2, methylates STAT1, activates STAT1, promotes trimethylation of IFN-stimulated gene-15, and restricts Hepatitis-B virus (HBV) production and pathogenesis via up regulation of its target gene, 05/September/2017, 11.53 am https://genomediscovery.org/wp-content/uploads/2017/09/EGCG-acts-as-an-antiviral-agent-against-Hepatitis-B-Virus-HBV-through-up-regulation-of-IFN-Stimulated-gene-15-MX2-expression1.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2017/09/EGCG-acts-as-an-antiviral-agent-against-Hepatitis-B-Virus-HBV-through-up-regulation-of-IFN-Stimulated-gene-15-MX2-expression1.jpg September 5, 2017 September 5, 2017

September 5, 2017

Molecular therapy for Metastatic cancers: Myrtenal, isolated from Taxus, increases the expression of DNA repair protein hMSH2 and the tumor suppressor protein CADM1 , inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 5/September/2017, 11.43 pm

Molecular therapy for Metastatic cancers: Myrtenal, isolated from Taxus, increases the expression of DNA repair protein hMSH2 and the tumor suppressor protein CADM1 , inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 5/September/2017, 11.43 pm https://genomediscovery.org/wp-content/uploads/2017/09/Myrtenal-increases-CADM1-and-hMsh2-expression-and-attenuates-tumor-progression.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2017/09/Myrtenal-increases-CADM1-and-hMsh2-expression-and-attenuates-tumor-progression.jpg September 5, 2017 September 5, 2017

September 4, 2017

Natural product-derived CDK4/6 pathway blockade enhances the efficacy of Cancer immunotherapy: A pharmacological mixture encompassing Linalool, 17-AAG, Simvastatin, Nimbolide, Deoxycholic acid and Trichostatin A (LASNDT) inhibits the expression of cell cycle protein CDK4/CDK6, increases levels of T-III IFNs, inhibits the proliferation of Treg cells, decreases DNMT1 expression, inhibits the expression of a number of immune evasion molecules, increases antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target genes, 5/September/2017, 3.37 am

Natural product-derived CDK4/6 pathway blockade enhances the efficacy of Cancer immunotherapy: A pharmacological mixture encompassing Linalool, 17-AAG, Simvastatin, Nimbolide, Deoxycholic acid and Trichostatin A (LASNDT) inhibits the expression of cell cycle protein CDK4/CDK6, increases levels of T-III IFNs, inhibits the proliferation of Treg cells, decreases DNMT1 expression, inhibits the expression of a number of immune evasion molecules, increases antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target genes, 5/September/2017, 3.37 am https://genomediscovery.org/wp-content/uploads/2017/09/LASND-and-Trichostatic-A-inhibit-CDK4.6-and-attenuate-tumor-progression.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2017/09/LASND-and-Trichostatic-A-inhibit-CDK4.6-and-attenuate-tumor-progression.jpg September 4, 2017 September 25, 2017

Introduction:What they say: A recent study from Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands has identified CMTM6 and CMTM4 as…

September 4, 2017

Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Streptomycin, the widely used drug in the treatment of tuberculosis, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 5/September/2017, 3.36 am

Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Streptomycin, the widely used drug in the treatment of tuberculosis, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 5/September/2017, 3.36 am https://genomediscovery.org/wp-content/uploads/2017/09/Streptomycin-inhibits-CHIKV-and-ZiKV-virus-production-through-down-regualtin-ofits-target-gene.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2017/09/Streptomycin-inhibits-CHIKV-and-ZiKV-virus-production-through-down-regualtin-ofits-target-gene.jpg September 4, 2017 September 5, 2017

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

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