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January 10, 2018

Lifespan extension therapy:  Candesartan, an angiotensin II receptor antagonist used mainly in the treatment of hypertension, may increase life span via up-regulation of its target gene BubR1, 10/January/2017, 7.02 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
January 10, 2018

Molecular therapy for Metastatic cancers: Torasemide, an anti-hypertensive drug, increases the expression of tumor suppressors PDCD4 and PTEN, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 10/January/2017, 6.52 pm

From Significance of the study to Public health relevance:  Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
January 10, 2018

Lifespan extension therapy: Atorvastatin (Trade name: Lipitor), a lipid-lowering agent, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 10/January/2017, 6.38 pm,

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
January 10, 2018

Vitamin-based Combinatorial therapy for reversing TIIDM: A pharmaceutical mixture encompassing Pyridoxamine and Sulforaphane (PMSFN) augments the expression of FGF19 and FGF1,   attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIIDM via up regulation of its target gene, 10/January/2017, 6.24 pm

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]
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