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December 6, 2018

Probiotic-based chemotherapy for “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: A pharmaceutical composition encompassing Valsartan, a medication used in the treatment of high blood pressure and congestive heart failure, and Lactobacillus Rhamnosus increases the expression of tumor suppressors genes, such as PTPN14, p12DOC1, TA-p73/p63, p53 and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene , 6/December/2018, 3.24 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
December 6, 2018

Hot water immersion therapy for lowering cholesterol, and triglycerides levels: Hot water immersion (at 39C for 1 hour) decreases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 6/December/2018, 3.09 pm

The significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 […]
December 5, 2018

Probiotic-based therapy for Metastatic cancers: Probiotic Lactobacillus rhamnosus decreases the expression of metastasis promoters ZBTB2 and PPM1F, inhibits cell cycle progression, and suppresses migration, invasion, and metastasis of cancer cells, via up regulation of its target gene, 5/December/2018, 10.44 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
December 5, 2018

Probiotic-based adjunctive therapy for Malaria: Probiotic Lactobacillus reuteri (DSM 17938 and ATCC PTA 5289) increases Ferroportin expression, decreases intracellular iron accumulation, inhibits cellular damage, prevents hemolysis, and inhibits malaria infection, via upregulation of its target gene, 5/December/2018, 9.35 pm

Introduction: What they say: A study from the Section on Human Iron Metabolism, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes […]
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