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January 31, 2018

Published by admin_auro at January 31, 2018

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Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: 9-Aminoacridine increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 31/January/2018, 11.13 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]

January 30, 2018

Published by admin_auro at January 30, 2018

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Ideas
NAFLD

Molecular therapy for Non-alcoholic fatty liver disease (NAFLD): Triiodothyronine, a thyroid hormone (T3), promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 30/January/2017, 11.41 pm

Significance of the study: Given that: (1) 15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]

January 30, 2018

Published by admin_auro at January 30, 2018

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Molecular therapy for anxiety and depression: Sertraline (Brand name: Zoloft, Lustral) decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 30/January/2018, 11.33 pm

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]

January 30, 2018

Published by admin_auro at January 30, 2018

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Lifespan extension therapy: Pantoprazole (Brand name: Protonix), a drug used in the treatment of stomach ulcers, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 30/January/2017, 11.25 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]