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July 31, 2017

Natural product-derived therapy for muscle atrophy and wasting: Capsaicin, isolated from Habanero Chilli and among others, increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via up regulation of its target gene, 31/July/2017, 10.22 pm

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard Lyon, INSA Lyon, Oullins, France […]
July 30, 2017

Natural product-derived regenerative therapy for muscle atrophy: Avicularin, isolated from Polygonum aviculare and among others, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 31/July/2017, 1.40 am

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes to multiple types of muscle […]
July 30, 2017

Natural product therapy for body weight control, energy homeostasis and TIIDM: A therapeutic mix encompassing Chlorogenic acid and Monascin, isolated from Green coffee and Edible fungi of the Monascus species, respectively, decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 31/July/2017, 12.48 pm

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
July 30, 2017

Natural product-derived PD-1 pathway activation for Pain therapy: Capsaicin, isolated from Chilli pepper,  increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gen, 31/July/2017, 12.17 am

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
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