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November 21, 2017

Natural product-derived combinatorial therapy for therapy-resistant cancers: A therapeutic mix encompassing encompassing   β-cryptoxanthin (BCX), Sodium butyrate, Fucoxanthin, Ganetespib, Rosuvastatin and Cyclophosphamide (BCXSFGRC) inhibits the expression of phospholipid glutathione peroxidase (GPX4), inhibits GPX4 signaling network and lipid peroxidase pathway, suppresses EMT protein ZEB1, increases sensitivity to anticancer therapy and prolongs survival via up regulation of its target gene, 21/November/2017, 10.49 pm

Introduction: What they say: A study from Broad Institute, Cambridge, Massachusetts, USA, Howard Hughes Medical Institute, Chevy Chase, Maryland and Department of Chemistry and Chemical Biology, […]
November 21, 2017

Life-extension therapy: Licorine, isolated from Clivia Miniata, Lycoris  (surprise lilies), and Narcissus, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 21/November/2017, 7.43 am

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
November 20, 2017

Natural product therapy for pulmonary arterial hypertension: Enoxolone (also known as glycyrrhetinic acid) , one of the main components of Liquorice, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 21/November/2017, 12.41 am

What they say:   A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
November 20, 2017

Natural product-derived therapy for anxiety and depression: Safranal, isolated from Saffron, Rooibos and among others, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 21/November/2017, 12.05 am

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
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