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November 27, 2017

Molecular therapy for Deafness: A therapeutic mix encompassing Chlorprothixene, Cholecalciferol, Ajoene and DIM (CECAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 27/November/2017, 10.17 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Molecular therapy for Deafness: A therapeutic mix encompassing Chlorprothixene, Cholecalciferol, Ajoene and DIM (CECAD)  increases the expression […]
November 27, 2017

Natural product therapy for Glaucoma: Formononetin, isolated from Trifolium Pratense, Maackia Amurensis/Amur Maackia, among others, increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma via down regulation of its target gene, 27/November/2017, 8.07 am

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, […]
November 27, 2017

Vitamin-based therapy for Non-alcoholic fatty liver disease (NAFLD): Calcitriol, a form of Vitamin-D, promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 27/September/2017, 6.31 am

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while only 6-25% of Asian populations suffer from it; […]
November 27, 2017

Natural product therapy for pulmonary arterial hypertension: Schisandrin B, one of the main components of Schisandra chinensis/Magnolia Vine, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 27/November/2017, 6.23 am

What they say:   A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
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