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June 23, 2017

Natural product-derived therapy for metastatic prostate cancer: Isorhapontigenin, isolated from sitka spruce (Picea sitchensis) and Aiphanes, inhibits the expression of CDC42, CDC42EP3, RAC1 and ARPC5, and GAS6, suppresses the expression of stem cell molecules CD44 and EZH2, promotes epithelial phenotype, suppresses tumorigenesis, migration, invasion, stem cell regeneration and metastasis via up regulation of its target gene, 23/June/2017, 11.33 pm

Introduction: What they say: A study from the Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Science Park, Texas 78957, USA […]
June 23, 2017

Electrical stimulus-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Electrical stimulus increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene Lin28, 24/June/2017, 10.15 pm

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows […]
June 23, 2017

Natural product-derived Anti-AXL therapeutics for enhancing the efficacy of chemotherapies: Combination of Hyperoside and Epigallocatechin-3- gallate, found in Drosera rotundifolia and Green tea, respectively, decreases the expression of the AXL receptor and its activating ligand, GAS6, increases the expression of a number of tumor suppressor genes, increases therapeutic index of anticancer drugs, suppresses tumorigenesis, migration, invasion, and metastasis via up regulation of its target gene, 23/June/2017, 9.49 pm

Introduction: What they say: A study from the Department of Radiation Oncology, Stanford University School of Medicine shows that “Inhibition of the GAS6/AXL pathway augments the […]
June 23, 2017

Natural product-derived therapy for Diabetic Kidney disease: Methyl Jasmonate (MeJA), isolated from Jasmine, decreases VEGF-B expression, inhibits lipid accumulation in Podocytes, promotes insulin signalling in Podocytes, induces insulin sensitivity, ameliorates renal dysfunction and alleviates diabetic kidney disease via down regulation of its target gene, 23/June/2017, 9.39 am

Introduction: What they say A study from the Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden shows that […]
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