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November 14, 2017
Published by admin_auro at November 14, 2017
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Molecular therapy for TIIDM and obesity-associated metabolic deficits: Victoza/Saxenda, a drug used in the treatment of TIIDM and Obesity,  increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 15/September/2017, 5.14 am

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that […]
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November 14, 2017
Published by admin_auro at November 14, 2017
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Molecular therapy for Deafness: A therapeutic mix encompassing 1,4-Naphthoquinone/Para-Naphthoquinone, Cholecalciferol, Ajoene and DIM (1,4 PNCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  and improves hearing loss via up regulation of its target gene, 15/November/2017, 5.43 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Molecular therapy for Deafness: A therapeutic mix encompassing 1,4-Naphthoquinone/Para-Naphthoquinone, Cholecalciferol, Ajoene and DIM (1,4 PNCAD)  increases […]
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November 14, 2017
Published by admin_auro at November 14, 2017
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Molecular therapy for body weight control, energy homeostasis and TIIDM: Atorvastatin, a lipid-lowering agent, decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 14/November/2017, 6.41 am

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
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November 14, 2017
Published by admin_auro at November 14, 2017
Categories

Molecular therapy for Metabolic diseases: Victoza/Saxenda, a glucagon-like peptide-1 receptor agonist that promotes insulin secretion, increases the expression of Caveolin-1, stabilizes insulin receptor, promotes insulin sensitivity, incrases vasorelaxation, and decreases the risk of hyperglycemia and TIIDM via up regulation of its target gene,  14/November/2017, 6.23 am

Introduction: What they say A study from the Institute for Molecular Systems Biology, ETH Zurich, Zurich, Switzerland shows that “MicroRNAs 103 and 107 regulate insulin sensitivity.” […]
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