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October 31, 2017

Natural product-based combinatorial therapy for ageing-associated diseases and Lifespan extension: A therapeutic mix encompassing iallyl disulfide, Isoorientin and Resveratrol (DIR) increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down regulation of its target gene, 31/September/2017, 10.35 am

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
October 31, 2017

Regenerative therapy for muscle atrophy: Simvastatin (Brand name: Zocor), a lipid lowering medication, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 31/October/2017, 10.25 am

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes […]
October 30, 2017

Natural product-based therapy for Inflammatory bowel disease(IBD): Carnosic acid, found in Rosmarinus officinalis and Common sage/Salvia officinalis, decreases the expression of oncostatin M, attenuates activation of oncostatin M- oncostatin M receptor pathway in inflamed colon tissues, inhibits inflammatory gene expression, attenuates colonic pathogenesis, and inhibits the progression of inflammatory bowel disease and colitis via down regulation of its target gene, 30/August/2017, 10.37 am

Introduction: What they say: A study from the Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, […]
October 30, 2017

Molecular therapy for Glaucoma: Netoglitazone, a blood glucose-lowering drug, increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma via down regulation of its target gene, 30/October/2017, 9.29 am

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, […]
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