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October 24, 2017

Natural product therapy for Diabetic nephropathy (DN):  Yangonin, isolated from Kava Kava, among others, increases Pyruvate kinase M2 (PKM2) expression, decreases toxic glucose metabolites, mitochondrial dysfunction and apoptosis, augments glycolytic flux and PGC-1α levels, improves metabolic abnormalities, albuminuria, glomerular pathology, and renal dysfunction and alleviates diabetic nephropathy via down regulation of its target gene, 25/October/2017, 1.04 am

Introduction: What they say A study from the Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA shows that “Pyruvate kinase M2 activation may […]
October 24, 2017

Lifespan extension therapy: Tetrahydrocannabinolic acid [THCA], found abundantly in Hemp Cannabis Sativa, among others,  may increase life span via up-regulation of its target gene BubR1, 25/October/2017, 12.38 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
October 24, 2017

Molecular therapy for body weight control, energy homeostasis and TIIDM:  Chenodeoxycholic acid (CDCA) [Trade name: Ursodiol] decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 25/October/2017, 12.01 am

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
October 24, 2017

Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: A pharmaceutical mixture encompassing Rivaroxaban and Asprin (RA) increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes via down regulation of its target gene, 24/October/2017, 11.24 pm

Introduction: What they say A study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was published, […]
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