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June 27, 2019

Published by admin_auro at June 27, 2019

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Curing autoimmune diabetes (TIDM) with HDAC (Histone deacetylase) inhibitors: Vorinostat-based therapy for autoimmune diabetes: Vorinostat (brand name: Zolinza and others), a histone deacetylase inhibitor used to treat cutaneous T-cell lymphoma (CTCL), increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 27/June/2019, 11.54 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]

June 25, 2019

Published by admin_auro at June 25, 2019

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Solving a few centuries-old mystery as to how Mustard oil ameliorates or fixes hearing impairment: Mustard oil-based therapy for Deafness and presbycusis: A therapeutic mix encompassing Allyl isothiocyanate (AITC), Cholecalciferol, Ajoene and DIM (AITCCAD) increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration, improves hearing loss, via up regulation of its target genes, 25/June/2019, 11.29 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Solving a few centuries-old mystery as to how Mustard oil ameliorates or fixes hearing impairment: Mustard oil-based […]

June 24, 2019

Published by admin_auro at June 24, 2019

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Eating ample amounts of fruit Pomegranate may extend your lifespan: Urolithin A (UA)-based combinatorial therapy for Lifespan extension: Urolithin A (UA), derived from Pomegranate, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, via up regulation of its target gene, 24/June/2019, 11.55 pm

What they say? A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]

June 23, 2019

Published by admin_auro at June 23, 2019

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Ideas
Pain

Solving a century-old puzzle as to how Mustard oil functions as a pain reliever: Mechanistic insights into how Mustard oil-derived compound functions as a pain medication: A pharmaceutical mixture encompassing Allyl IsoThioCynate (AITC), derived from mustard seed or oil, increases the expression of PD-L1, decreases the expression of Cox-2, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 23/June/2019, 11.19 pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]