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September 24, 2017

Natural product-derived therapy for tuberculosis: Withaferin A (WA), isolated form Ashwagantha/Withania sominifera, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 25/September/2017, 12.05 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
September 24, 2017

Antiviral therapy for HIV virus: Combvir [Zidovudine (ZDV)/Azidothymidine (AZT) and Lamivudine], an anti-HIV drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 24/September/2017, 11.59 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Antiviral therapy for HIV virus: Combvir [Zidovudine (ZDV)/Azidothymidine (AZT) and Lamivudine], an anti-HIV drug, increases Heme oxygenase […]
September 24, 2017

Natural product-derived antiviral therapy against Neuroinvasive West Nile virus: Solosodine, isolated from Solanum melongena L, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 24/September/2017, 11.53pm

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of […]
September 24, 2017

Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Epigallocatechin gallate (EGCG), isolated from Green tea, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 24/September/2017, 11.45 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
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