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April 13, 2017

Natural product-derived therapy for brain repair and Lifespan extension: Avicularin, a flavonol isolated from Polygonum aviculare, Rhododendron aureum and Taxillus kaempferi, increases VGF and BDNF expression, promotes Oligodendrocytes (OP) proliferation, triggers myelination, reverts neural damage, produces antidepressant like effects, and prolongs lifespan via up-regulation of its target gene, 13/April/2017, 7.09 pm

What they say: Introduction:   A recent study from the Department of Biochemistry & Molecular Pharmacology, Smilow Research Center, Howard Hughes Medical Institute, NYU School of […]
April 12, 2017

Cardiac rejuvenation therapy: Spermidine suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy via up regulation of its target gene, 12/April/2017, 10.56 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Cardiac rejuvenation therapy: Spermidine suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy […]
April 12, 2017

Natural product-derived therapy for prostate cancer bone metastasis: γ-Bisabolene, one of the main components of Cardamom, cubeb, oregano, and lemon among others, inhibits the expression of Monoamine oxidase A (MAOA), inhibits Shh-IL6-RANKL signaling network, suppresses tumor-stromal interactions, reduces prostate cancer metastasis and prolongs survival via up regulation of its target gene, 12/April/2017, 1.34 pm

Introduction: What they say: A study from the Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA shows that “MAOA-Dependent Activation of […]
April 12, 2017

Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Mangiferin (MA), found in Mangoes and Iris Unguicularis among others, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target, 12/April/2017, 9.05 am

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows […]
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