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September 24, 2017

Published by admin_auro at September 24, 2017

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Natural product-derived antiviral therapy against Neuroinvasive West Nile virus: Solosodine, isolated from Solanum melongena L, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 24/September/2017, 11.53pm

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of […]

September 24, 2017

Published by admin_auro at September 24, 2017

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Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Epigallocatechin gallate (EGCG), isolated from Green tea, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 24/September/2017, 11.45 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]

September 23, 2017

Published by admin_auro at September 23, 2017

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Natural product-derived therapy for anxiety and depression: Berberine, isolated from Berberis vulgaris, among others, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 24/September/2017, 12. 07 am

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]

September 23, 2017

Published by admin_auro at September 23, 2017

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Cancer
Ideas

Natural product-derived CDK4/6 pathway blockade enhances the efficacy of Cancer immunotherapy: A pharmacological mixture encompassing Shikonin, Amitriptyline, Rosustatin,Cholecalciferol, Hypericin, Nimpolide, PEITC, Linalool and Salinomycin (SARCHNPLS) inhibits the expression of cell cycle protein CDK4/CDK6, increases levels of T-III IFNs, inhibits the proliferation of Treg cells, decreases DNMT1 expression, inhibits the expression of a number of immune evasion molecules, increases antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target genes, 23/September/2017, 11.51 pm

Introduction:What they say: A recent study from Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands has identified […]