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August 6, 2017
Published by admin_auro at August 6, 2017
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Natural product-derived therapy for EVI-1-Overexpressing Acute Myeloid Leukemia: Sulforaphane, isolated from Broccoli, decreases the expression of MECOM/EVI-1 and its down target genes, including CKMT-1, alters Arginine-creatine metabolism, inhibits mitochondrial respiration, depletes ATP levels, and promotes regression of EVI-1-overexpressing AML via up regulation of its target gene, 6/August/2017, 10.52 pm

Introduction: What they say: A study from the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; […]
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August 6, 2017
Published by admin_auro at August 6, 2017
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Mild Hypothermia therapy for Cardiomyopathy: Mild Hypothermia  increases the expression of miR-208a, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 6/August/2017,  10.40 pm

Introduction: What they say A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart […]
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August 6, 2017
Published by admin_auro at August 6, 2017
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Natural product therapy for KRAS/LKB1-mutant lung cancer: Ivermecitin increases the levels of tumor suppressor proteins, inhibits the expression of urea cycle enzyme carbamoyl phosphate synthetase-1 (CSP1), decreases pyrimidine pools, stalls DNA synthesis, and inhibits the progression of KRAS/LKB1-mutated lung cancers via up regulation of its target gene, 6/August/2017, 10.29 pm

Introduction: What they say A study from the Children’s Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas 75390, USA; Department of Pediatrics, UT Southwestern Medical Center, […]
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August 6, 2017
Published by admin_auro at August 6, 2017
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Natural product-derived therapy for glucose homeostasis and TIIDM: Mangiferin , isolated from Mangoes, increases Barr2 expression, augments the functional activity of CAMKII, increases insulin secretion, promotes glucose homeostasis, prevents progression to TIIDM and ameliorates obesity-associated metabolic deficits via down regulation of its target gene, 6/August/2017, 10.28 pm

Introduction: What they say A study from the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland […]
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