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April 28, 2017

Natural product therapy for Diabetic nephropathy (DN): Oleanolic acid, found in Jawa apple, Olea Europaea, and Mirabilis Jalaba among others, increases Pyruvate kinase M2 (PKM2) expression, decreases toxic glucose metabolites, mitochondrial dysfunction and apoptosis, augments glycolytic flux and PGC-1α levels, improves metabolic abnormalities, albuminuria, glomerular pathology, and renal dysfunction and alleviates diabetic nephropathy via down regulation of its target gene, 28/April/2017, 11.36 am

Introduction: What they say A study from the Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA shows that “Pyruvate kinase M2 activation may […]
April 28, 2017

Natural product therapy for glucose homeostasis and TIIDM: Isoorientin (or homoorientin), a flavone isolated from Passion flower, Swertia japonica, Terminalia myriocarpa, and the Açaí among others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 28/April/2017, 9.01 am

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
April 27, 2017

Natural product therapy for TIIDM and Metabolic defects: Ursolic acid, found in Mirabilis Jalapa, Ocimum Sanctum, and apple peels among others, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 27/April/2017, 11.30 pm

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC […]
April 27, 2017

Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Serotonin reuptake inhibitor (SRI) antidepressant Fluoxetine (Trade names: Prozac and Sarafem) increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene Lin28, 27/April/2017, 6.58 pm

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows […]
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