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March 4, 2017

Molecular therapy for Metastatic cancers: α-Solanine, isolated from Flowers and Fruits of bittersweet nightshade, decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up regulation of its target gene, 4/March/2017, 7.21 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
March 3, 2017

Natural product-derived antiviral therapy for HIV virus: Epigallocatechin gallate, one of the main components of Green tea, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 3/March/2017, 11.11 pm

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]
March 3, 2017

Natural product-derived therapy for EVI-1-Overexpressing Acute Myeloid Leukemia: Naringenin, isolated from Grapefruit, decreases the expression of MECOM/EVI-1 and its down target genes, including CKMT-1, alters Arginine-creatine metabolism, inhibits mitochondrial respiration, depletes ATP levels, and promotes regression of EVI-1-overexpressing AML via up regulation of its target gene, 3/March/2017, 10.53 pm

Introduction: What they say: A study from the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; […]
March 3, 2017

Natural product-derived therapy for glucose homeostasis and TIIDM: Fisetin, isolated from strawberries, apples, persimmons, onions, cucumbers, acacias and among others, increases Barr2 expression, augments the functional activity of CAMKII, increases insulin secretion, promotes glucose homeostasis, prevents progression to TIIDM and ameliorates obesity-associated metabolic deficits via down regulation of its target gene, 3/March/2017, 3.35 pm

Introduction: What they say A study from the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland […]
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