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March 8, 2017

Natural product-derived therapy for Metastatic cancers: Curcumin, one of the main components of turmeric, decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up regulation of its target gene, 8/March/2017, 9.34 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
March 8, 2017

Molecular therapy for triple-negative breast tumors: PAPD5 (PAP-Associated Domain-Containing Protein 5/(Poly(A) RNA Polymerase D5, Non-Canonical) increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 8/March/2017, 8.25 am

Introduction: What they say  A study from the Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA shows that […]
March 8, 2017

Natural product therapy for Breast Cancer: Shikonin, one of the major components of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), increases the level of tumor suppressor p53, decreases the expression of metastasis promoter Snail1, inhibits the proliferation of tumor-initiating cells, suppresses the progression of metastatic breast cancer, and supports tumor relapse-free survival in breast cancer patients, 8/March/2017, 7.31 am

Introduction: What they say:  A study from the Division of Molecular Medicine and Genetics, Department of Internal Medicine, The Life Sciences Institute, University of Michigan, Ann […]
March 7, 2017

Natural product-derived therapy for Hepatocellular carcinoma: δ-tocotrienol (a form of Vitamin-E) attenuates phosphoenolpyruvate carboxykinase (PEPCK1) sumoylation, stabilizes PEPCK1 levels, promotes gluconeogenesis, inhibits glycolysis and attenuates the progression of hepatocellular carcinoma via up regulation of its target gene, 7/March/2017, 2.27 pm

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]
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