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August 21, 2017
Published by admin_auro at August 21, 2017
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Natural product-derived Combinatorial therapy targeting CMTM6/4-PD-L1 pathway enhances the efficacy of Cancer immunotherapy: A therapeutic mix encompassing Artemisinin , Capsaicin and Kaempferol, inhibits the expression of transmembrane protein CMTM6/CMTM4, increases interferon-IFNγ signalling, augments antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 21/August/2017, 11.41 pm

Introduction:What they say: A recent study from Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Plesmanlaan, CX Amsterdam, The Netherlands has identified CMTM6 and […]
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August 21, 2017
Published by admin_auro at August 21, 2017
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Small molecule-based exercise mementics therapy for Metabolic disease: Curcumin, derived from Turmeric, increases PPARδ  and Foxo1 levels, inhibits glucose catabolism, preserves glucose levels, stimulates FA catabolism, delays the onset of hypoglycemia and boosts endurance exercise via down regulation of its target gene, 21/August/2017, 1.27 am

Introduction: What they say  A study from Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA shows […]
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August 20, 2017
Published by admin_auro at August 20, 2017
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Molecular therapy for glioblastoma: A therapeutic mix encompassing N-Acetylcysteine (NAC), β-Cryptoxanthine, and Magnolol inhibits the expression of JMJD6, impairs functioning of transcription elongation machinery, inhibits the proliferation of glioblastoma cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 21/August/2017, 12.33 am

Introduction: What they say: A study from the Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Ohio, USA shows that “Transcription elongation factors […]
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August 20, 2017
Published by admin_auro at August 20, 2017
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Molecular therapy for Metastatic cancers: Myrtenal, isolated  from Taxus, increases the expression of metastasis suppressors TAp63 and TPM1, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 21/August/2017, 12.20 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
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