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July 1, 2017

Cardiac rejuvenation therapy: Deoxyactein, isolated from the root and rhizomes of black cohosh (Cimicifuga racemosa), suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy via up regulation of its target gene, 1/July/2017, 10.53 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Cardiac rejuvenation therapy: Deoxyactein, isolated  from the root and rhizomes of black cohosh (Cimicifuga racemosa), […]
July 1, 2017

Natural product-derived therapy for heart regeneration and repair: Moringin, isolated from Moringa Oleifera, increases Agrin expression, activates Yap and ERK-mediated signaling, replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 1/July/2017, 10.02 pm

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, Durham, North […]
June 30, 2017

Natural product-derived therapy for Metastatic cancers: Dihydroartemisinin (DHA), a derivative of Artemisinin isolated from Artemisia Annua L, increases the expression of metastasis suppressors TAp63 and TPM, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 1July/2017, 12.48 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half […]
June 30, 2017

Natural product-based therapy for Inflammatory bowel disease (IBD): Shikonin, isolated from Zi Cao, decreases the expression of oncostatin M, attenuates activation of oncostatin M- oncostatin M receptor pathway in inflamed colon tissues, inhibits inflammatory gene expression, attenuates colonic pathogenesis, and inhibits the progression of inflammatory bowel disease and colitis via down regulation of its target gene, 7/July/2017, 12.35 am

Introduction: What they say: A study from the Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, […]
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