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Dr.Boomi

Anti-telomerase cancer therapy: MiRNA-1246 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of its target gene, 8/November/2016, 10.47 pm
Anti-telomerase cancer therapy: MiRNA-1246 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of its target gene, 8/November/2016, 10.47 pm 150 150

Introduction: What they say:  The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This…

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Natural product therapy for Bone disorders: Parkia-javanica extract inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 8/November/2016, 10.43 pm
Natural product therapy for Bone disorders: Parkia-javanica extract inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 8/November/2016, 10.43 pm 150 150

Introduction:  A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.”…

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Interleukin therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: IL-17 (Interleukin-17) promotes an insulin-sensitized state via up-regulation of reprogramming protein Lin28, 8/November/2016, 10.33 am
Interleukin therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: IL-17 (Interleukin-17) promotes an insulin-sensitized state via up-regulation of reprogramming protein Lin28, 8/November/2016, 10.33 am 150 150

Introduction: A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates glucose metabolism.” This study was…

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Natural product therapy for triple-negative breast tumors: Aloe vera extract increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 8/November/2015, 10.29 pm
Natural product therapy for triple-negative breast tumors: Aloe vera extract increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 8/November/2015, 10.29 pm 150 150

Introduction: What they say A study from the Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA shows that “PIM1 kinase inhibition as…

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Natural product-based PD-1 pathway blockade for Human cancer therapy: Neem leaf extract inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 8/November/2016, 10.15 pm
Natural product-based PD-1 pathway blockade for Human cancer therapy: Neem leaf extract inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 8/November/2016, 10.15 pm 150 150

Introduction:What they say:  A recent study from Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD 21218, United States shows that “TGF-β1-Mediated Smad3 Enhances PD-1 Expression on…

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Natural product therapy for KRAS-mutant lung cancer: Moringa oleifera (MO) extract decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene, 8/November/2016, 5.22 pm
Natural product therapy for KRAS-mutant lung cancer: Moringa oleifera (MO) extract decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene, 8/November/2016, 5.22 pm 150 150

What they say:  A recent study from the Department of Cell Biology, University of Texas Southwestern Medical Center, Texas 75390, USA shows that XPO1 can be pharmacologically targeted in KRAS-mutant lung cancer.…

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