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May 20, 2017

Natural product-derived therapy for Metastatic cancers: Shikonin, isolated from Zi Cao, decreases the expression of metastasis promoters, such as Fibronectin-I, RhoE and Zeb1/2, increases the expression of metastasis suppressor E-Cadherin, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 20/May/2017, 11.45 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
May 20, 2017

Natural product therapy for middle aged TIIDM patients: Phyllanthus emblica L, also known as Indian Gooseberry/Amla, decreases DNA-PK expression, suppresses phosphorylation of HSP90a, increases AMPK activity, augments mitochondrial biogenesis and energy metabolism, promotes weight loss and exercise endurance and alleviates TIIDM via down regulation of its target gene, 20/May/2017, 11.41 pm

Introduction: What they say A study from the Laboratory of Obesity and Aging Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD […]
May 20, 2017

Laminar shear stress-based therapy for Inflammatory bowel disease:Laminar shear stress promotes NFKB-p50/p65 dimer formation, induces inflammatory gene expression downstream of RelA/p65, inhibits colonic pathogenesis, and stalls the progression of inflammatory bowel disease and colitis via down regulation of its target gene, 20 May/2017, 9.18 am

Introduction: What they say: A study from the Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg, University of Mainz, Obere Zahlbarer Str, Mainz, […]
May 19, 2017

Natural product-derived (exercise mementics) therapy for Metabolic disease: Formononetin, isolated from Astragalus membranaceus (AM), increases PPARδ levels, inhibits glucose catabolism, preserves glucose levels, stimulates FA catabolism, delays the onset of hypoglycemia and boosts endurance exercise via down regulation of its target gene, 19/May/2017, 10.14 pm

Introduction: What they say A study from the Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for […]
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