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March 19, 2017
Published by admin_auro at March 19, 2017
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Natural product-derived therapy for pulmonary fibrosis: Berberine, found in Berberis, Berberis aristata, Hydrastis canadensis, Phellodendron amurense, and Argemone mexicana, among others, decreases miR-34 expression, increases Sirtuin-1 expression, suppresses tumor suppressor p53 acetylation, prevents apoptosis in Alveolar epithelial cell (AEC), and improves pulmonary fibrosis via down regulation of its target gene, 19/March/2017, 04.27 pm

What we say:  Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived therapy for pulmonary fibrosis: Berberine, found in Berberis, Berberis aristata, Hydrastis canadensis, Phellodendron amurense, […]
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March 19, 2017
Published by admin_auro at March 19, 2017
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Natural product-based Lifespan extension therapy: Polydatin (PD), isolated from the root and rhizome of herb Polygonum cuspidatum, activates autophagy and extends lifespan via up regulation of ATG5, 19/March/2017, 9.45 am

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
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March 19, 2017
Published by admin_auro at March 19, 2017
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Natural product-derived antiviral therapy for HIV virus: Triptolide, isolated from herb Thunder God Vine, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 19/March/2017, 8.24 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived antiviral therapy for HIV virus: Triptolide, isolated from herb Thunder God […]
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March 19, 2017
Published by admin_auro at March 19, 2017
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MiRNA-based Life-span extension therapy: MiR-761 may increase lifespan by suppressing mTOR pathway, 19/March/2016, 7.49 am

What is known:  It has been shown earlier that decreasing the expression/activity of mTOR increases overall mammalian lifespan, suggesting that mTOR inhibitors may function as “longevity […]
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