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February 5, 2017

Life-extension therapy: Orphan nuclear receptor Nur77/NGFI-B inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 5/February/2017, 6.47 pm

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
February 5, 2017

Natural product-based therapy for Metastatic tumors: Formononetin, an isoflavone found in the roots of astragalus membranaceus, Trifolium pratense, Glycyrrhiza glabra, and Pueraria lobata, increases the expression of tumor suppressor gene PDCD4 and promotes apoptosis of tumor cells via down regulation of its target gene, 5/February/2017, 6.23 pm

From Significance of the study to Public health relevance:  Given that: (1) Cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
February 5, 2017

Molecular therapy for Myocardial Infarction: Ethyl Pyruvate (EP) inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 5/February/2017, 8.51 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
February 5, 2017

Natural product-derived therapy for glucose homeostasis and TIIDM: Guggulsterone, isolated from Commiphora mukul resin, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 5/February/2017, 7.30 am

Introduction: What they say  A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
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