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June 29, 2017
Published by admin_auro at June 29, 2017
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Natural product/vitamin-based Combination therapy for PTEN-deficient cancer: A therapeutic mix encompassing Dihydromyricetin, Cholecalciferol and Metformin decreases the expression of CHD1, increases the expression of a number of tumor suppressor genes, inhibits pro-survival TNF-NF-kB gene network, and suppresses tumorigenesis of PTEN-deficient cancer, 29/April/2017, 11.59 pm

Introduction: What they say: A study from the Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA shows that “Synthetic […]
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June 29, 2017
Published by admin_auro at June 29, 2017
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Natural product-based therapy for TIIDM and obesity-associated metabolic deficits: Artesunate, a derivative of Artemisinin isolated from Artemisia Annua, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 29/May/2017, 11.58 pm

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent […]
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June 29, 2017
Published by admin_auro at June 29, 2017
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Natural product-derived therapy for Metastatic cancers: Dihydroartemisinin (DHA), a derivative of Artemisinin isolated from Artemisia Annua L, increases the expression of metastasis promoters TIMP3 and CCM3/KRIT1, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 29/June/2017, 11.56 pm pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half […]
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June 29, 2017
Published by admin_auro at June 29, 2017
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Natural product-derived therapy for Chronic Myeloid leukaemia (CML): Curcumin, isolated from Turmeric, decreases the expression of Musashi2, inhibits cytosolic aminotransferase BCAT1 expression, decreases the intracellular production of BCAAs (Branched-chain amino acids), increases the expression of tumor suppressor genes, promotes differentiation of CML cells, and inhibits cancer progression in Myeloid leukemia via up-regulation of its target gene, 29/May/2017, 11.56 pm

Introduction: What they say: A study from the Department of Biochemistry-Molecular Biology, Franklin College of Arts and Sciences, The University of Georgia, Athens, Georgia 30602, USA; and […]
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