Immune enhancement therapy: Galectin-3 increases SOX2 expression and promotes innate immunity against bacterial infection via down regulation of its target gene, 21/September/2016, 6.40 am

A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity against microbial infection.” This study was published in the 2 March 2015 issue of the Journal “Nature Immunology” [the number one journal in immunological research with an impact factor of  24.973] by Drs. Zusen Fan, […]

Natural product therapy for Human Cancer: Agaricus blazei Murill (AbM) suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down regulation of its target gene, 20/September/2016, 8.09 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Undisclosed information: How Agaricus blazei Murill (AbM) extract  suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This study provides mechanistic insights into how TPP1 […]

Natural product Life-extension therapy: Siegesbeckia glabrescens extract inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via up regulation of its target gene, 20/September/2016, 7.41 am

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.” This study was published in the 2 October 2009 issue of the Journal “Science” (I.F: 31.477 ) by Prof Dominic J. Withers, Dr. Selman C and others. On the foundation of […]

Natural product therapy for Human Cancer: Olea tree leaf extract suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down regulation of its target gene, 19/September/2016, 3.53 pm

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Undisclosed information: How Olea tree leaf extract  suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This study provides mechanistic insights into how TPP1 […]

Natural product Life-extension therapy: Gingko biloba extract inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via up regulation of its target gene, 19/September/2016, 3.23 pm

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.” This study was published in the 2 October 2009 issue of the Journal “Science” (I.F: 31.477 ) by Prof Dominic J. Withers, Dr. Selman C and others. On the foundation of […]

Natural product therapy for pulmonary arterial hypertension: Olive tree leaf extract inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 18/September/2016, 10.53 am

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in General Medicine with an I.F of 28.054] by Prof. Thistlethwaite PA, Li X and others. On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product therapy for pulmonary arterial hypertension: Olive […]