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March 11, 2019

Repurposing the anti-analgesic agent Celecoxib into an anti-HIV agent: Celecoxib (trade name: Celebrex), a selective cox-2 (Cyclooxygease-2) inhibitor, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 11/March/2019, 11.46 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Repurposing the anti-analgesic agent Celecoxib into an anti-HIV agent: Celecoxib (trade name: Celebrex), a selective cox-2 […]
March 10, 2019

Ribonucleic acid-based therapy for Diabetes Mellitus: LncRNA TUG1 augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM, via upregulation of its target gene, 10/March/2019, 2.15 pm

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]
March 10, 2019

Probiotic-based therapy for autoimmune diabetes: Probiotic  Dulac ATP increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 10/March/2019, 1.47 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical […]
March 10, 2019

Molecular therapy for inflammation and arthritis:  Methylene blue(MB) (trade names: Urelene blue, Provayblue, Proveblue) increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up-regulation of its target genes, 10/March/2018, 1.29 pm

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that […]
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